NCT04206163

Somatostatin Receptor Imaging in Acute Myocarditis and Cardiac Sarcoidosis

Somatostatin Receptor Imaging in Inflammatory Heart Disease

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 78 (actual)
• Sponsor: Vastra Gotaland Region · Other Government
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

This prospective imaging study investigates the diagnostic ability of Gallium-68 DOTA-TOC (68Ga-DOTA-TOC) positron emission tomography/computed tomography (PET/CT) in the clinical work-up of patients with 1) clinically suspected acute myocarditis (n=30-40) and 2) clinically suspected cardiac sarcoidosis (n=30-40) using clinical diagnostic criteria as well as endomyocardial biopsy as reference. Furthermore, 68Ga-DOTA-TOC PET/CT findings will be compared with results from contrast-enhanced magnetic resonance imaging (MRI) and in case of cardiac sarcoidosis even Fluorine-18 fluorodeoxyglucose (18F-FDG) PET/CT, which are both performed as part of the clinical routine work-up.

Conditions

• Acute Myocarditis
• Cardiac Sarcoidosis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	68Ga-DOTA-TOC PET/CT	Somatostatin receptor imaging
BIOLOGICAL	Blood sample	Analysis of inflammatory biomarkers

Timeline

• Start date: 2020-01-20
• Primary completion: 2024-06-24
• Completion: 2024-06-24
• First posted: 2019-12-20
• Last updated: 2024-09-27

Locations

1 site across 1 country: Sweden