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RecruitingNCT04204499

Analysis of Screen-detected Lung Cancers' Genomic Traits

Status
Recruiting
Phase
Study type
Observational
Enrollment
526 (estimated)
Sponsor
University College, London · Academic / Other
Sex
All
Age
50 Years – 77 Years
Healthy volunteers
Not accepted

Summary

Prospective, observational cohort study of patients undergoing surgical resection for low dose CT (LDCT) screen-detected lung cancer (detected through the SUMMIT study- ClinicalTrials.gov Identifier: NCT03934866/ lung screening programmes), in which translational research is a fundamental aspect.

Detailed description

The ASCENT study seeks to examine the genomic signatures of screen-detected cancers, in order to categorise the biological behaviour of such lesions and correlate this against non-invasive biological and radiological parameters. From these data, the plan is to explore strategies to characterise LDCT-detected cancers through non-invasive means, which the researchers believe may prove key in mitigating potential screening-associated harms.

Conditions

Timeline

Start date
2020-08-10
Primary completion
2025-08-30
Completion
2026-03-30
First posted
2019-12-19
Last updated
2025-07-25

Locations

2 sites across 1 country: United Kingdom

Source: ClinicalTrials.gov record NCT04204499. Inclusion in this directory is not an endorsement.

Analysis of Screen-detected Lung Cancers' Genomic Traits (NCT04204499) · Clinical Trials Directory