NCT04202302

Vaginal Profile in IVF/ICSI and Impact on Clincal Outcome

The Impact of Vaginal Profile During Ovarian Stimulation on the IVF/ICSI Outcome: a Prospective Observational Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Academic / Other
• Sex: Female
• Age: 20 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

Vaginal flora is closely related to female reproductive health. Previous studies have suggested that the composition of the vaginal flora is related to the pregnancy outcomes, and abnormalities in the vaginal flora lead to a decrease in the success rate of IVF. During the IVF treatment, the hormone level changes far exceed the physiological level. What changes will happen to the vaginal flora? Does IVF treatment itself affect the vaginal flora and affect outcomes? This study used prospective cohort study to show the changes in vaginal flora during conventional IVF treatment, providing more evidence for revealing the relationship between vaginal flora and infertility treatment outcomes.

Conditions

• Vaginal Flora Imbalance

Interventions

Type	Name	Description
PROCEDURE	IVF/ICSI	ovarian stimulation ，vaginal disinfection of flushing

Timeline

• Start date: 2019-08-06
• Primary completion: 2020-03-01
• Completion: 2020-03-01
• First posted: 2019-12-17
• Last updated: 2019-12-18

Locations

1 site across 1 country: China