Clinical Trials Directory

Trials / Terminated

TerminatedNCT04201782

Long-term Follow-up of HIV Subjects Exposed to SB-728-T or SB-728mR-T

Long-Term Follow-up of HIV-Infected Subjects Treated With Autologous T-Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases (SB-728-T or SB-728mR-T)

Status
Terminated
Phase
Study type
Observational
Enrollment
38 (actual)
Sponsor
Sangamo Therapeutics · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Long-term follow-up of HIV-infected subjects who received SB-728-T or SB-728mR-T. Enrolling subjects will be followed for a total of 12 years.

Detailed description

Subjects infected with HIV who have received therapy with SB-728-T or SB-728mR-T will be eligible to participate in this trial. There will be no treatment in this long-term follow-up study. Subjects who choose to enroll into this extension study will be evaluated for a total of 12 years.

Conditions

Interventions

TypeNameDescription
DRUGThere are no disallowed treatmentsGenetic: SB-728-T or SB-728mR-T No study drug is administered in this study. Subjects who received SB-728-T or SB-728mR-T in a previous trial will be evaluated in this trial for long-term safety and efficacy.

Timeline

Start date
2011-03-18
Primary completion
2023-07-17
Completion
2023-07-17
First posted
2019-12-17
Last updated
2024-01-26

Locations

4 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04201782. Inclusion in this directory is not an endorsement.