Clinical Trials Directory

Trials / Unknown

UnknownNCT04198480

A Clinical Trial to Assess the Efficacy and Safety of JMT103 in Patients With Refractory HCM

A Phase I/II, Single Arm, Open Label, Multi-center Clinical Trial to Assess the Efficacy and Safety of JMT103 in Patients With Refractory Hypercalcemia of Malignancy

Status
Unknown
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
17 (estimated)
Sponsor
Shanghai JMT-Bio Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine the potential of JMT103 to treat hypercalcemia of malignancy in patients with elevated serum calcium who do not respond to recent treatment with intravenous bisphosphonates.

Detailed description

This is a Phase I/II, Single arm, Open Label, Multi-center Clinical Trial to Assess the Efficacy and Safety of JMT103 in Patients With refractory Hypercalcemia of Malignancy.

Conditions

Interventions

TypeNameDescription
DRUGJMT1032 mg/kg subcutaneously (SC) every 4 weeks with a loading dose of 2 mg/kg SC on study days 8 and 15.

Timeline

Start date
2020-01-24
Primary completion
2021-07-30
Completion
2021-12-31
First posted
2019-12-13
Last updated
2019-12-13

Source: ClinicalTrials.gov record NCT04198480. Inclusion in this directory is not an endorsement.