NCT04194983

The Effect of Fish Oils With Dairy or Plant Based Lipids on Mitochondrial and Physical, and Cognitive Function, in Elderly Humans

To Examine the Effect of Dietary Supplementation With Fish Oils With Dairy or Plant Based Lipids on Mitochondrial, Physical, and Cognitive Function, in Elderly Humans

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (actual)
• Sponsor: Maastricht University · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to determine whether dairy or plant based fats combined with fish oils can alter skeletal muscle mitochondrial, physical, and cognitive function.

Detailed description

Physical and cognitive function decline as we get older and this may be due to changes within the mitochondria, organelles that regulate energy production in our cells. The ability of the mitochondria to produce energy can be affected by diet, and the composition of lipids in the cell is an important factor in determining how effective our mitochondria are. Dairy and plant based lipids differ in composition and therefore may differ in their ability to affect mitochondrial function when combined with fish oils (FO). The primary objective of this study is to determine whether supplementation with dairy or plant based fats combined with fish oils can alter skeletal muscle mitochondrial function. Additional exploratory objectives are 1) skeletal muscle and physical function and 2) cognitive function.

Conditions

• Ageing
• Mitochondrial Function
• Physical Function
• Cognitive Function

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Fish oils and dairy fat	12-weeks, 3x per day
DIETARY_SUPPLEMENT	Fish oils and plant fat	12-weeks, 3x per day

Timeline

• Start date: 2019-12-11
• Primary completion: 2020-10-15
• Completion: 2020-10-15
• First posted: 2019-12-11
• Last updated: 2020-11-13

Locations

2 sites across 1 country: Netherlands