NCT04194840

Transplant Wellness Clinic for Elderly or High Risk Patients Undergoing BMT

Pilot Study to Develop a Transplant Wellness Clinic for Elderly or High Risk Patients Undergoing Blood and Marrow Transplantation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Case Comprehensive Cancer Center · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

As the average age of individuals undergoing stem cell transplant continues to increase, challenges associated with balancing the side effects of cancer treatments while also managing other medical conditions develop. Studies have shown these individuals develop more treatment related side effects and take longer to leave the hospital due to complications. The purpose of this study is to develop a multiple provider clinic that will help identify any additional needs in the more complicated and generally older transplant patient population. If needed, this clinic will recommend interventions or referrals to the appropriate specialties to the participant and the transplant physician for the participant before your transplant procedure. Examples of potential areas of improvement include a course of physical therapy, nutritional supplements, or modifications of medications, among others with the goal to make your transplant safer and to decrease length of time in the hospital.

Detailed description

This is a supportive interventional study to assess frailty in at risk geriatric cancer patients undergoing stem cell transplant and to determine if specific interventions are feasible and will improve overall outcomes. A total of 20 participants will be enrolled in this study with the first 10 participants limited to myeloma or lymphoma patients who meet eligibility criteria and are candidates for autologous transplantation. The second 10 participants enrolled will be either allogeneic or autologous stem cell transplant candidates who meet eligibility criteria. The objectives of this study are as follows: * To pilot a comprehensive multidisciplinary geriatric assessment clinic. * To determine whether a comprehensive geriatric assessment (outside of physical therapy assessment) can be performed in a time efficient manner. The goal is to complete all questionnaires and the multidisciplinary assessments in \<90 minutes. * To assess participant and physician satisfaction * To determine if interventions recommended in the clinic are achievable for each participant * Examples of interventions could include, medication changes, management of depression, dietary modifications, physical therapy three times a week, etc. * To determine if participation in the transplant wellness clinic reduces length of stay and readmission rate compared to historical controls at our institution

Conditions

• Stem Cell Transplant Complications
• Myeloma
• Lymphoma
• Allogeneic and Autologous Stem Cell Transplant

Interventions

Type	Name	Description
OTHER	physical therapy consult	Physical therapy consult to assess physical functioning on a separate office visit prior to attending the Transplant Wellness Clinic. Full evaluation that incorporates several tools to measure the risk of falling and to assess mobility and strength
OTHER	Cognitive Assessment	Montreal cognitive assessment (MoCA) and the Blessed Orientation-Memory-Concentration Test (BOMC)
OTHER	Cancer Aging Research Group (CARG) assessment	CARG assessment - utilized to capture information about a participant's medical history as well as functional, cognitive, and psychosocial status
OTHER	Medication Review	Medication Review via Beers Assessment
OTHER	Nutrition assessment	Nutrition assessment Via Mini Nutrition Assessment (MNA)
OTHER	Laboratory studies	Laboratory studies including urine toxicology screen, C-reactive protein, albumin, pre-albumin, vitamin D
OTHER	Patient satisfaction questionnaire	Patient satisfaction questionnaire
OTHER	Physician Questionnaire	Physician Questionnaire: Questionnaire to learn about physician satisfaction with information received from reports and participant questionnaires.
OTHER	Patient follow-up questionnaire	Patient follow-up questionnaire: Questionnaire to learn more about participant opinions concerning the clinic and the quality of care received during visits with specialists

Timeline

• Start date: 2021-05-01
• Primary completion: 2024-06-27
• Completion: 2025-03-28
• First posted: 2019-12-11
• Last updated: 2025-08-05

Locations

1 site across 1 country: United States