Trials / Completed
CompletedNCT04193865
Hemofilter Life Span, ECLS And/or CRRT
Hemofilter Life Span and Filtration of Inflammatory Markers in Patients Receiving Extracorporeal Life Support And/or Continuous Renal Replacement Therapy
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 10 (actual)
- Sponsor
- Medical University of South Carolina · Academic / Other
- Sex
- All
- Age
- 0 Days – 17 Years
- Healthy volunteers
- Not accepted
Summary
The goal of this project to better understand the immune-modulatory effects of continuous renal replacement therapy (CRRT) in neonatal and pediatric patients, particularly those receiving extracorporeal life support (ECLS). Little is known about the effects of CRRT in this particular population and improved knowledge will be useful clinically and may lead to novel therapeutic approaches and improved outcomes for these critically ill patients.
Detailed description
Via collection of serum and ultrafiltrate samples, the invesitgators will examine how hemofilter lifespan alters the filtration of pro- and anti-inflammatory cytokines.
Conditions
- Kidney Diseases
- Acute Injury of Kidney
- Renal Failure
- Renal Insufficiency
- Neonatal Renal Disorder (Disorder)
Timeline
- Start date
- 2020-01-09
- Primary completion
- 2023-03-01
- Completion
- 2024-03-25
- First posted
- 2019-12-10
- Last updated
- 2024-10-28
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT04193865. Inclusion in this directory is not an endorsement.