Trials / Completed
CompletedNCT04193319
Effect of Fluconazole on PK of Fluzoparib in Healthy Male Subjects
Study on the Pharmacokinetics of Fluconazole on Single-center, One-arm, Open and Fixed Sequences of Fluzoparib in Healthy Male Subjects
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 20 (actual)
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd. · Industry
- Sex
- Male
- Age
- 35 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to evaluate the Effect of fluconazole on the Pharmacokinetics of Fluzoparib in Healthy male Adults
Detailed description
Subjects received oral Fluzoparib 20 mg after D1 single meal, D2-D4 for washing period, D5 started oral fluconazole 400 mg/day/day after meal, continuous administration for 6 days to D10, D8 meal After oral administration of fluconazole 400 mg, a single oral dose of Fluzoparib 20 mg was given immediately.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Fluzoparib | PARP inhibitor |
| DRUG | Fluconazole | inhibitor |
Timeline
- Start date
- 2019-07-19
- Primary completion
- 2019-09-12
- Completion
- 2019-09-12
- First posted
- 2019-12-10
- Last updated
- 2019-12-10
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT04193319. Inclusion in this directory is not an endorsement.