NCT04192669

Heart Rate Variability as a Clinical Marker in a Population of Anxio-depressive Patients

Study of Heart Rate Variability as a Clinical Marker in a Population of Anxio-depressive Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 44 (actual)
• Sponsor: Tatiana Besse-Hammer · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The heart rate (HR) is regulated by the autonomic nervous system (ANS) and results from a balance between the sympathetic nervous system (SNS) that accelerates the heart rate and the parasympathetic nervous system that slows the HR via the vagus nerve. Low HRV is linked to poor emotional and cognitive regulation. Values for HRV are generally lower in depressed patients. The aim of this study is to determine how HRV could be a clinical marker that can be used in routine psychiatry practice in patients with anxio-depressive disorders, to determine the severity of symptoms and the degree of response to treatment.

Conditions

• Anxio Depressive Disorder

Interventions

Type	Name	Description
DEVICE	Heart rate monitoring	The heart rate will be recorded and calculated by a heart rate monitor (Polar H10, Finland) located on the chest. The recording is done over a period of 5 minutes, the patient being in a sitting position, without any particular stimulus, in a quiet room. The recording is transferred via the HRV Logger application. Any ectopic beats and artifacts are automatically identified and replaced by values interpolated by the investigator, if necessary. The Kubios HRV Premium Software is used for all calculations.

Timeline

• Start date: 2019-11-11
• Primary completion: 2021-07-13
• Completion: 2021-07-13
• First posted: 2019-12-10
• Last updated: 2022-07-19

Locations

1 site across 1 country: Belgium