NCT04190017

Comparison of Brain Volumes Measured by 2D USG and MRI

Comparison of Brain Volumes of Preterm Infants Measured by Two Dimensional Ultrasonography and Cranial Magnetic Resonance Imaging

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 25 (estimated)
• Sponsor: Ankara City Hospital Bilkent · Academic / Other
• Sex: All
• Age: 1 Day – 3 Months
• Healthy volunteers: Not accepted

Summary

Cranial USG is simple and easy method to assess preterm infant brain. Some studies showed that brain volumes of preterm infants could be calculated by measurement of 2D distances. Our aim in this study was to compare brain volume obtained by USG and MRI.

Detailed description

All preterm infants less than 32 weeks of gestational age undergo cranial USG examination routinely at least, in the first week of life, at the end of first month and corrected age 36 weeks and 40 weeks. We will performa all USG mesurements with measureing intracranial hegiht, anteroposterior diameter, biparietal diamater, ventriccular height, thalamo-occipital distance and ventricular index. We will calculate the brain volume as a spheric geometric shape than we will calculate two ventricles as conical shapes. Absolute brain volume will be calculating by substracting two ventricles from total brain volume. At 40 weeks of age we will perform a cranial MRI to show exact brain volume and we will ccompare two different methods.

Conditions

• Central Nervous System Vulnerabilities in Preterm Infants

Interventions

Type	Name	Description
OTHER	Cranial MRI	Cranial MRI

Timeline

• Start date: 2019-11-01
• Primary completion: 2021-12-30
• Completion: 2022-03-30
• First posted: 2019-12-09
• Last updated: 2021-01-13

Locations

1 site across 1 country: Turkey (Türkiye)