NCT04188717

Incidence, Risk Factors, Predictors and Survival for Neurological Complications After Liver Transplantation

Incidence, Risk Factors, Predictors and Survival for Neurological Complications After Liver Transplantation- A Retrospective Analysis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 253 (actual)
• Sponsor: Institute of Liver and Biliary Sciences, India · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Liver transplantation is the definitive treatment in patients with chronic liver disease. Neurological complications (NC) occur commonly after liver transplantation. The investigators aim to evaluate the incidence, risk factors and predictors of neurological complications in both living donor and deceased donor transplantation done in the hospital. Between January 2011 to December 2016, 253 liver transplant recipients were recruited for this study. The investigators recorded the incidence of neurological complications, their median time of onset, their relationship with etiology of chronic liver disease, and the risk factors for the complications. The investigators also studied the relationship of neurological complications with duration of hospital and ICU stay, and survival. Using multivariate forward regression analysis , the investigators developed a scoring system for prediction of neurological complications in liver transplantation.

Conditions

• Liver Transplant; Complications
• Neurologic Complication
• Postoperative Complications

Timeline

• Start date: 2010-01-01
• Primary completion: 2016-12-31
• Completion: 2017-01-01
• First posted: 2019-12-06
• Last updated: 2019-12-10