NCT04188288

Neurofeedback in Individuals With Substance Use Disorders

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Yale University · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to train individuals with opioid use disorder to control their brain activity in a way that has been associated with their symptoms. Participants in the experimental group will be given direct feedback regarding their brain activity while they are undergoing functional magnetic resonance imaging (fMRI) scanning, and will try to learn to control their brain activity during these feedback sessions. A separate group of participants will be given a control form of feedback that we do not believe can have clinical benefits. Our primary hypothesis is that the neurofeedback training will reduce opioid use and clinical features of opioid use disorder more than the control feedback.

Conditions

• Opioid-Related Disorders

Interventions

Type	Name	Description
DEVICE	Experimental feedback	Participants provided with feedback of target brain activation patterns (for example, in the form of a line graph) and will be instructed to try to make the line go up or down.
DEVICE	Control feedback	Participants provided with control type of feedback (for example, in the form of a line graph) and will be instructed to try to make the line go up or down.
DEVICE	fMRI	fMRI will be used to assess brain activity

Timeline

• Start date: 2021-07-01
• Primary completion: 2023-03-15
• Completion: 2023-03-15
• First posted: 2019-12-05
• Last updated: 2024-09-25
• Results posted: 2024-09-25

Locations

1 site across 1 country: United States