Trials / Completed
CompletedNCT04185623
Time Lag for Oocyte Denudation: A Better Choice for ICSI Outcome?!
Time Lag for Oocyte Denudation:Is it a Better Choice for ICSI Outcome?!
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 300 (actual)
- Sponsor
- Ahmed Saad · Academic / Other
- Sex
- Female
- Age
- 24 Years – 37 Years
- Healthy volunteers
- Not accepted
Summary
This study aiming to investigate if difference in the timing of cumulus removal post retrieval would have any critical impact on fertilization and embryonic development.
Detailed description
Patients under 37 year old who were treated with controlled ovarian stimulation for ICSI were randomly divided into 2 groups; Group A: Oocytes were denudated immediately after oocyte retrieval , Group B: Oocytes were denudated 2 hours after retrieval and both groups were microinjected at 4 hours from ovum pickup. Microinjection was performed on all matured oocytes only and they were cultured to blastocyst stage.The rates of maturation, fertilization, good quality blastulation, chemical pregnancy and clinical pregnancy were analysed and compared between the two groups.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | denudation time lag | The time between ovum pickup and denudation of oocyte |
Timeline
- Start date
- 2019-06-01
- Primary completion
- 2020-10-01
- Completion
- 2020-12-01
- First posted
- 2019-12-04
- Last updated
- 2022-09-21
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT04185623. Inclusion in this directory is not an endorsement.