Clinical Trials Directory

Trials / Completed

CompletedNCT04184856

Binges and Neural Variability

What is Driving the Binge in Binge Eating Disorder? Variability in Brain Response to Reward and the Escalation of Consumption

Status
Completed
Phase
Study type
Observational
Enrollment
61 (actual)
Sponsor
University Hospital Tuebingen · Academic / Other
Sex
All
Age
18 Years – 69 Years
Healthy volunteers
Accepted

Summary

People who suffer from binge eating disorder experience recurrent episodes of binge eating.During these episodes, they consume an unusually large amount of food in a short amount of time and experience loss of control over eating. However, why such binge eating episodes occur is still largely unknown. This makes it difficult to develop targeted treatments. In this project, the experimenters are investigating the brain mechanisms that give rise to the disorder. They hypothesize that the binge eating episodes are due to an increased variability in reward processing, which they will assess repeatedly over days. They will test this hypothesis using mathematical models based on behavioural and MRI measurements that are related to the processing of rewards.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTfMRI(Imaging while) performing reward related tasks.

Timeline

Start date
2019-12-06
Primary completion
2021-05-31
Completion
2021-05-31
First posted
2019-12-04
Last updated
2021-08-11

Locations

1 site across 1 country: Germany

Source: ClinicalTrials.gov record NCT04184856. Inclusion in this directory is not an endorsement.