Clinical Trials Directory

Trials / Unknown

UnknownNCT04182581

A Study of BCMA/CD19 Dual-Target CAR-T Cell Immunotherapy for Relapsed or Refractory Multiple Myeloma

A Study of B-cell Maturation Antigen/Cluster of Differentiation Antigen 19 Dual-Target Chimeric Antigen Receptor T Cell Immunotherapy for Relapsed or Refractory Multiple Myeloma

Status
Unknown
Phase
EARLY_Phase 1
Study type
Interventional
Enrollment
18 (estimated)
Sponsor
Xijing Hospital · Academic / Other
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

The study is an early, open, single-centered trial. The purpose of this study is to evaluate the safety and persistence of BCMA/CD19 dual-target CAR-T cell immunotherapy in relapsed or refractory MM. The study will include 18 subjects to receive BCMA/CD19 dual-target CAR-T therapy.

Conditions

Interventions

TypeNameDescription
BIOLOGICALBCMA/CD19 Dual-Target CAR-TBCMA/CD19 Dual-Target CAR-T target both BCMA and CD19. The subjects will receive CAR-T as one dose. The dosage ranges from 5×10\^4 to 3×10\^5 CAR+T/Kg.

Timeline

Start date
2019-10-15
Primary completion
2020-09-01
Completion
2021-05-01
First posted
2019-12-02
Last updated
2019-12-02

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT04182581. Inclusion in this directory is not an endorsement.