NCT04181463

Nasal Inhalation of Isopropyl Alcohol for the Treatment of Nausea in Patients With Cancer

Inhalation Approaches to Nausea: A Randomized Controlled Trial

• Status: Not Yet Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 112 (estimated)
• Sponsor: M.D. Anderson Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this research study is to understand the effect of inhalation approaches in reducing nausea in cancer patients.

Detailed description

In this study, inhalation of a study solution will be compared to inhalation of placebo, both in the form of preparation pads (a small square of material that contains the solution). Isopropyl alcohol may be a part of the preparation pads. A placebo is not a drug. It looks like the study solution but is not designed to treat any disease or illness. It is designed to be compared with the study solution to learn if the study solution has any real effect. Inhalation of the study solution may help to control your nausea. Future patients may benefit from what is learned. There may be no benefits for you in this study. Your participation is completely voluntary. Before choosing to take part in this study, you should discuss with the study team any concerns you may have, including side effects, potential expenses, and time commitment.

Conditions

• Malignant Neoplasm

Interventions

Type	Name	Description
DRUG	Isopropyl Alcohol	Given via nasal inhalation
OTHER	Placebo	Given via nasal inhalation
OTHER	Questionnaire Administration	Ancillary studies

Timeline

• Start date: 2025-11-05
• Primary completion: 2025-12-30
• Completion: 2025-12-30
• First posted: 2019-11-29
• Last updated: 2025-10-31

Locations

1 site across 1 country: United States