Trials / Completed
CompletedNCT04180644
Skin Tape Transcriptome Methods in Children
Evaluation of Novel Skin Tape Transcriptome Methods in Children With Atopic Dermatitis and Healthy Controls
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 20 (actual)
- Sponsor
- National Jewish Health · Academic / Other
- Sex
- All
- Age
- 4 Years – 12 Years
- Healthy volunteers
- Accepted
Summary
This pilot study will evaluate new methods for the collection, storage, shipment, and RNA extraction of skin tape specimens from children with atopic dermatitis (AD) that will facilitate the multi-center SunBeam Birth Cohort study. Additionally, this pilot study will test new methods for the generation of whole transcriptome sequencing data from skin tape RNA and whether these data reflect the transcriptional state of the skin in health and disease.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Skin tape strips | Skin tape strips will be collected from lesional and non-lesional skin. Adhesive skin sampling discs will be firmly pressed against the skin in a hairless location (not the face) followed by lifting it free of the skin. These discs will then be used to evaluate proteins and lipids in the upper layers of skin. |
Timeline
- Start date
- 2020-01-10
- Primary completion
- 2020-02-05
- Completion
- 2020-02-05
- First posted
- 2019-11-27
- Last updated
- 2020-04-13
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT04180644. Inclusion in this directory is not an endorsement.