Trials / Completed
CompletedNCT04178330
Tomotherapy as Primary Radiotherapy for Multipule Brain Metastases
Tomotherapy as Primary Radiotherapy for Multipule Brain Metastases:A Single Arm, Single Center,Phase II Trial
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 82 (actual)
- Sponsor
- Chinese Academy of Medical Sciences · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
This clinical trial was designed to investigate the efficiency and toxicity of tomotherapy as primary radiotherapy for multiple brain metastases.
Detailed description
This is a single-arm, single center, phase II trial to investigate the feasibility and toxicity of tomotherapy as primary radiotherapy for multiple brain metastases(≥3 lesions).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| RADIATION | tomotherapy | Whole brain radiation (WBRT) with 38-40Gy in 20 fractions and concurrent boost of 60-70Gy of the lesions. TMZ is used if necessary: concomitant TMZ: 75mg/m2 adjuvant TMZ: 150mg/ m2\*5d, q28d, up to 6cycles. |
Timeline
- Start date
- 2014-09-01
- Primary completion
- 2017-06-13
- Completion
- 2017-06-13
- First posted
- 2019-11-26
- Last updated
- 2019-11-26
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT04178330. Inclusion in this directory is not an endorsement.