NCT04178018

Transvaginal Ultrasound and Photoacoustic Imaging of Ovary

Transvaginal Ultrasound and Photoacoustic Imaging of the Ovary

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 310 (estimated)
• Sponsor: Washington University School of Medicine · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study is being conducted to validate if photoacoustic imaging potentially reduces benign surgeries without compromising cancer detection sensitivity. The study will also explore whether using the photoacoustic imaging/ultrasound technique has any potential with early ovarian cancer detection in a group of high risk patients.

Detailed description

In primary and secondary objectives, the investigators will consent patients who are at risk for ovarian cancer, or who have an ovarian mass possibly suggestive of a malignancy and are counseled to undergo oophorectomy. Patients will be identified by the GYN physicians and consented by the study coordinator prior to the date of the scheduled surgical procedure. In exploratory objectives, the investigators will consent patients who are at risk for ovarian cancer and wish to be followed before making decision to undergo prophylactic oophorectomy. Patients will be identified based on the eligibility criteria by the physicians and consented by the study coordinator prior to the follow up studies.

Conditions

• Ovary; Anomaly

Interventions

Type	Name	Description
DEVICE	Photoacoustic imaging	-Emerging technique in which a short-pulsed laser beam penetrates diffusively into a tissue sample
DEVICE	Ultrasound	-The ultrasound is being used in conjunction with the photoacoustic imaging

Timeline

• Start date: 2020-02-09
• Primary completion: 2027-01-31
• Completion: 2027-01-31
• First posted: 2019-11-26
• Last updated: 2025-11-28

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study