NCT04176640

Quantifying Brain Injury on Computed Tomography in Hospitalized Children

Quantifying Brain Injury on Computed Tomography in Hospitalized Children: a Prospective Trial

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 425 (actual)
• Sponsor: The Hospital for Sick Children · Academic / Other
• Sex: All
• Age: 1 Day – 17 Years
• Healthy volunteers: Not accepted

Summary

Lay Summary: To evaluate a novel early diagnostic tool for hospitalized children with traumatic brain injury. The Problem: Children who present with decreased level of consciousness after injury require urgent medical attention determined by the type and the severity of injury. Unfortunately, history and physical findings are often unreliable in the first hours after hospitalization, the period in which urgent management decisions must be made for their treatment. The Solution: A promising tool developed for measuring detectable evidence of traumatic brain injury on routine brain scans. The tool combines features invisible to the human eye but detectable by computer software with expert knowledge.This study will evaluate how well the tool can perform in a real health care setting. It is believed that it will greatly improve the efficacy and quality of care provided to children after traumatic brain injury.

Detailed description

To evaluate a novel early neuroimaging diagnostic tool for hospitalized children with traumatic brain injury. This tool is used to detect evidence of traumatic brain injury on routine brain scans. The tool combines features invisible to the human eye but detectable by computer software with expert knowledge.This study will evaluate how well the tool can perform in a real health care setting. It is believed that it will greatly improve the efficacy and quality of care provided to children after traumatic brain injury.

Conditions

• Trauma, Brain
• Pediatric

Timeline

• Start date: 2015-10-20
• Primary completion: 2019-12-31
• Completion: 2019-12-31
• First posted: 2019-11-25
• Last updated: 2019-11-25