NCT04169204

Very Old Intensive Care Patients - Perfusion

Very Old Intensive Care Patients - Perfusion (VIPPER)

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 47 (actual)
• Sponsor: Heinrich-Heine University, Duesseldorf · Academic / Other
• Sex: All
• Age: 80 Years
• Healthy volunteers: Not accepted

Summary

Shock is a frequent, etiologically heterogeneous and often lethal clinical condition of intensive care medicine. This is particularly true for very old intensive care patients (VIPs), who are among the fastest-growing subgroups of all intensive care unit (ICU) patients and who suffer from a significantly impaired outcome. In addition to the treatment of the causes of shock, current therapeutic approaches focus on the stabilization of vital parameters, which in general all reflect macrocirculatory measured values such as blood pressure. In contrast, a disturbance of the microcirculation (blood circulation of the smaller blood vessels \<100 µm) is only poorly measurable and delayed. The last generation of AVA-Software (MicroVisionMedical) will calculate different parameters about the capillary densitiv and perfusion in a user-independent way. VIPPER investigates whether a non-invasive measurement of microcirculation using the sublingual mucosa in very old intensive care patients in shock leads to faster recognition and specific treatment of organ dysfunctions. Secondly, this study checks whether this measurement predicts outcome.

Conditions

• Microcirculation
• Intensive Care
• Very Old Intensive Care Patients

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Measurement of microcirculation	As a simple clinical test, every patient will receive the assessment capillary refill time and mottling-score. Additionally, repetitive measurements of lactate will be done. The SDF-camera (MicroVision Medical®, Amsterdam, Netherlands) will measure sublingual microcirculation at different time points (Admission and 24h).

Timeline

• Start date: 2020-05-19
• Primary completion: 2023-05-31
• Completion: 2024-05-30
• First posted: 2019-11-19
• Last updated: 2024-01-09

Locations

1 site across 1 country: Germany