Trials / Terminated
TerminatedNCT04168294
The Influence of Sedation for Endoscopy on Cognitive Function
- Status
- Terminated
- Phase
- —
- Study type
- Observational
- Enrollment
- 200 (actual)
- Sponsor
- Shanghai Jiao Tong University School of Medicine · Academic / Other
- Sex
- All
- Age
- 20 Years – 64 Years
- Healthy volunteers
- Not accepted
Summary
It is commonly recommended that patients should refrain from driving for 24 hours after sedation for endoscopy，however，this recommendation has been queried recently．To investigate the effect of sedation on early postoperative cognitive function in patients undergoing endoscopy.
Detailed description
One hundred adult patients undergoing sedative esophagogastroduodenoscopy ( EGD) were randomly recruited，and another 100 adult patients undergoing conventional（without sedation） EGD were served as controls． All patients had an education level more than 9 years． Cognitive function was assessed by Montreal Cognitive Assessment（MoCA）1 week before EGD exam, 10 mins before propofol sedation or the beginning of endoscopic procedure, 30mins after EGD exam, and 2 week after exam.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Propofol | patients in sedation group will be intravenous injected propofol in bolus |
| DEVICE | endoscopy | endoscopy system |
Timeline
- Start date
- 2019-11-14
- Primary completion
- 2019-11-14
- Completion
- 2019-11-14
- First posted
- 2019-11-19
- Last updated
- 2019-11-19
Locations
1 site across 1 country: China
Regulatory
- FDA-regulated drug study
- FDA-regulated device study
Source: ClinicalTrials.gov record NCT04168294. Inclusion in this directory is not an endorsement.