NCT04168047

Are Sleeping Disorders Associated With Visceral Hypersensitivity in Irritable Bowel Syndrome Patients ?

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: University Hospital, Rouen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Visceral hypersensitivity is frequent in IBS population up to 60% and is correlated with severity and altered quality of life. Sleeping troubles are most frequent in IBS population. Insomnia is a frequent disorder with an important cost for healthcare. Insomnia could decrease pain threshold. Visceral hypersensitivity was never measure in patients with insomnia. The hypothesis is IBS patients with insomnia probably have lower visceral pain threshold. The objective is to assess pain threshold during a barostat procedure in in IBS patients with or without insomnia in comparison with healthy volunteers or patients with insomnia. If the hypothesis are confirmed, insomnia should be look at in IBS patients and its treatments could improve visceral hypersensitivity and IBS symptoms.

Conditions

• Irritable Bowel Syndrome

Interventions

Type	Name	Description
PROCEDURE	Barostat procedure	Pressure threshold will be measured during the barostat procedure
OTHER	Anxiety and Depression Evaluation	Anxiety and Depression will be measured using HAD anxiety and depression scale
OTHER	Assessment of sleep quality	Sleep quality will be measured using Pittsburg sleep quality index

Timeline

• Start date: 2020-09-22
• Primary completion: 2025-11-12
• Completion: 2025-11-12
• First posted: 2019-11-19
• Last updated: 2026-02-06

Locations

1 site across 1 country: France