NCT04167592

Benzydamine Hydrochloride Gargle in Reducing Propofol for ERCP

Effectivity of Benzydamine Hydrochloride Gargle to Reduce Propofol Consumption in Endoscopic Retrograde Cholangiopancreatography Procedure

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 72 (actual)
• Sponsor: Indonesia University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

It was a study aimed to determine the effectivity of benzydamine hydrochloride gargling in reducing propofol consumption in the Endoscopic Retrograde Cholangiopancreatography (ERCP) procedure.

Detailed description

The study was approved by Ethics Committee of Indonesia University. It was a single-blind randomized clinical trial at Cipto Mangunkusumo Hospital - Jakarta during August to September 2018. 72 subjects were recruited and randomly assigned into 2 groups. Patients in group B were given 0.15% mouthwash with benzydamine hydrochloride prior to procedure while patients in group C were given mouthwash with 15 ml of water. Cumulative propofol consumption per minute per kg body weight, and incidence of postoperative sore throat were measured for each group.

Conditions

• ERCP

Interventions

Type	Name	Description
DRUG	Benzydamine Hydrochloride 0.15% Oral Rinse	Benzydamine Hydrochloride 0.15% Oral Rinse was used to gargle prior to Endoscopic Retrograde Cholangiopancreatography (ERCP) procedure.
DRUG	Water	Water was used to gargle prior to Endoscopic Retrograde Cholangiopancreatography (ERCP) procedure.

Timeline

• Start date: 2018-08-01
• Primary completion: 2018-09-01
• Completion: 2018-10-01
• First posted: 2019-11-19
• Last updated: 2019-11-19

Locations

1 site across 1 country: Indonesia