NCT04167319

A Feasibility Study Investigating Chemotherapy-induced Neuropathy Using Multi-frequency Tactilometry and Patient-reported Outcomes (PRO)

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 32 (actual)
• Sponsor: Zealand University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Chemotherapy induced peripheral neuropathy (CIPN) is among the most feared side effects to cancer treatment. The development of CIPN can lead to discontinuation or omission of antineoplastic drugs, possibly affecting efficacy of cancer treatment. There is a lack of knowledge about the natural course of CIPN and to this date, there are no available methods for the early detection of CIPN. With no effective prevention or treatment options, the condition has severe impact on patient quality of life and healthcare expenditure. This study will investigate the natural course of paclitaxel- and oxaliplatin induced peripheral neuropathy using novel diagnostic techniques. Multi-frequency vibrational technology has provided an objective method for the early detection of diabetic neuropathy. Our study will test the feasibility of this method within the field of clinical oncology and CIPN.

Conditions

• Chemotherapy-induced Peripheral Neuropathy

Interventions

Type	Name	Description
OTHER	QST and PRO measurements during treatment	We will observe the natural course of CIPN using multiple measurements

Timeline

• Start date: 2019-11-20
• Primary completion: 2021-06-30
• Completion: 2021-09-30
• First posted: 2019-11-18
• Last updated: 2020-09-02

Locations

1 site across 1 country: Denmark