NCT04165603

Fluorescence-navigated Thoracoscopy for Detection of Small Pulmonary Nodules

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 352 (estimated)
• Sponsor: Peking University People's Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Fluorescence-navigated thoracoscopic imaging with indocyanine green (ICG) is a novel technique for detection of small pulmonary nodules other than traditional radiography or intraoperative palpation. As a non-targeted fluorescent contrast agent, ICG accumulates in tumors by the enhanced permeability and retention effect (EPR), making the lesions fluoresce under fluorescent imaging. However, the optimal dosage and injection time of ICG are still under exploration. Hence, we perform this study in humans made up of four groups to determine the optimal time and dose.

Conditions

• Pulmonary Nodule, Solitary
• Pulmonary Nodule, Multiple

Interventions

Type	Name	Description
PROCEDURE	Preoperative Infusion of Indocyanine Green	preoperatively infuse indocyanine green through peripheral vein

Timeline

• Start date: 2018-12-18
• Primary completion: 2021-06-01
• Completion: 2021-06-01
• First posted: 2019-11-18
• Last updated: 2019-11-18

Locations

1 site across 1 country: China