Clinical Trials Directory

Trials / Completed

CompletedNCT04164888

Phase 2a Study to Assess CIVI 007 in Patients on a Background of Statin Therapy

A Placebo-controlled, Randomized, Phase 2a, Study to Assess the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of CIVI 007 in Patients on a Background of Stable Statin Therapy

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
49 (actual)
Sponsor
Civi Biopharma, Inc. · Industry
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

Evaluation of the clinical profile (lipid efficacy, safety and PK) across a number of doses of CIVI 007, a PCSK9 inhibitor. Patients to be evaluated will be on a stable background of statin therapy with or without ezetimibe.

Conditions

Interventions

TypeNameDescription
DRUGCIVI 007hypercholesterolemia agent

Timeline

Start date
2019-11-11
Primary completion
2020-06-18
Completion
2020-11-17
First posted
2019-11-15
Last updated
2025-02-13
Results posted
2025-02-13

Locations

7 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04164888. Inclusion in this directory is not an endorsement.