NCT04164797

Study of Endostar Combined With TP Regimen for Esophageal Cancer

A Clinical Study of Endostar Combined With TP Regimen for Chemoradiotherapy in Esophageal Cancer

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 402 (estimated)
• Sponsor: Second Affiliated Hospital of Xi'an Jiaotong University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

a randomized controlled trial of endostar combined with TP regimen(liposomal paclitaxel-carboplatin) for chemoradiotherapy in esophageal squamous cell carcinoma(Ⅱ-Ⅲ)

Detailed description

This study was a controlled clinical trial.A total of 402 patients with pathologically confirmed esophageal squamous cell carcinoma would be enrolled.Patients were randomly divided into two group ,with 201 in the treatment group and 201 in the control group.The treatment group was treated with endostar,chemotherapy (liposomal paclitaxel-carboplatin)and concurrent radiotherapy.The control group was treated with chemotherapy (liposomal paclitaxel-carboplatin)and concurrent radiotherapy .The efficiency and safety would be evaluated. The objective response rate and progress free survival would be analyzed.This data of this study might provide a more effective treatment for esophageal squamous cell carcinoma

Conditions

• Patients With Esophageal Cancer(Ⅱ-Ⅲ)

Interventions

Type	Name	Description
DRUG	endostar+chemoradiotherapy	antiangiogenic drug+chemoradiotherapy
OTHER	chemoradiotherapy	chemoradiotherapy

Timeline

• Start date: 2019-11-25
• Primary completion: 2021-07-13
• Completion: 2021-07-13
• First posted: 2019-11-15
• Last updated: 2019-11-25

Locations

1 site across 1 country: China