NCT04159727

Gut Microbiota Dysbiosis and Translocation During IBD and Parkinson

Gut Microbiota Dysbiosis and Translocation Within Patients Suffering From Diseases Associated With Increased Intestinal Barrier Permeability : IBD and Parkinson

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: Hôpital Européen Marseille · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Inflammatory bowel diseases (IBD) and Parkinson disease (PD) are complex and multifactorial pathologies. Gut microbiota seems to play an active role. Indeed the digestive microbiota of patients with IBD or PD exhibits different compositions compared with asymptomatic subjects. Bacterial translocation from gut to blood has been reported.

Detailed description

The investigators designed a case-control study to investigate the digestive microbiota and bacterial translocation during IBD and PD. The investigators want to evaluate gut microbiota bacteria involved in dysbiosis and bacterial translocation during IBD and PD. The investigators want to identify bacterial populations that can serve as biomarkers for clinical practice.

Conditions

• Inflammatory Bowel Diseases
• Parkinson Disease

Interventions

Type	Name	Description
OTHER	stool and blood analysis	High throughput sequencing and quantitative PCR

Timeline

• Start date: 2019-03-28
• Primary completion: 2020-02-13
• Completion: 2020-02-13
• First posted: 2019-11-12
• Last updated: 2025-09-16

Locations

1 site across 1 country: France