NCT04157790

Efficacy of the CARE Rule Associated With the HEART Score in Patients With Emergency Chest Pain

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 2,153 (actual)
• Sponsor: University Hospital, Angers · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Acute coronary syndrome (ACS) is a major public health problem and its diagnosis remains a challenge for the emergency physician. The European Society of Cardiology recommends a troponin dosage and renew it if necessary during any suspicion of ACS. However, the criteria leading to initiate a diagnostic procedure during chest pain are imprecise. The fear is, on the one hand, to miss a potentially vital diagnosis and, on the other hand, to expose a large number of patients to unnecessary examinations. The CARE rule (also known as HEAR score) seems to streamline this first step. It assigns a value of 0 to 2 using 4 items: Characteristic of pain, Age, Risk factors and Electrocardiogram (ECG). The search for an ACS is not justified if the sum of the points is \<2 (negative rule) and, inversely, a troponin determination must be carried out if the sum is \> 1 (positive rule). The aim of the study is to demonstrate the safety and interest of the CARE rule associated with the HEART score to streamline ACS's diagnostic approach to thoracic pain in emergencies departments.

Detailed description

Data collected in this study are not anticipated to be published in a data repository. However, data will be shared per requested need to researchers, upon presentation of a structured protocol, when approved by the competent ethic committee and approved by the steering committee.

Conditions

• Chest Pain

Interventions

Type	Name	Description
OTHER	CARE score	CARE score calculation

Timeline

• Start date: 2022-01-10
• Primary completion: 2023-05-05
• Completion: 2023-09-19
• First posted: 2019-11-08
• Last updated: 2023-10-23

Locations

11 sites across 2 countries: Belgium, France