NCT04156932

Closure of the Uterine Artery at Its Origin vs at the Cervix: a Randomized Trial

Closure at the Origin of the Uterine Artery vs. Closure at the Cervico-isthmic Level in Laparoscopic Hysterectomy: a Randomized Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (actual)
• Sponsor: Ospedale degli Infermi di Biella · Academic / Other
• Sex: Female
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

One of the fundamental surgical steps in patients undergoing laparoscopic hysterectomy is the closure of the uterine artery, this vessel provides the greatest blood supply to the uterus. This step can be done in two ways: the surgeon can choose to interrupt the blood flow by closing the uterine artery in its last part, close to the uterus, or the surgeon can develop the anatomical spaces around the uterus into the deep pelvis, closing it to its origin, maintaining a minimally invasive approach in both cases. Scientific research has tried to establish whether one of the two modalities is the best in reducing intraoperative blood loss and possible complications, but currently there is not enough evidence to recommend an approach rather than another. The investigator has therefore decided to evaluate the results at the end of a laparoscopic hysterectomy in a scientifically rigorous manner.

Conditions

• Anatomy
• Laparoscopy
• Uterine Artery
• Hysterectomy

Interventions

Type	Name	Description
PROCEDURE	uterine artery closure	Interruption the uterine blood flow by closing the uterine artery at its cervical-isthmic part or at its origin.

Timeline

• Start date: 2019-12-01
• Primary completion: 2020-08-31
• Completion: 2020-08-31
• First posted: 2019-11-08
• Last updated: 2021-02-08

Locations

1 site across 1 country: Italy