NCT04153435

Calcium for Out-of-Hospital Cardiac Arrest

Calcium for Out-of-Hospital Cardiac Arrest - A Randomized, Double-Blind, Placebo-Controlled Trial

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 397 (actual)
• Sponsor: Lars Wiuff Andersen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is an investigator-initiated, multicenter, randomized, placebo-controlled, parallel group, double-blind, superiority trial of calcium during adult out-of-hospital cardiac arrest. 430 adult patients with out-of-hospital cardiac arrest receiving at least one dose of adrenaline will be enrolled. The primary outcome is sustained return of spontaneous circulation and key secondary outcomes include survival at 30 days and survival at 30 days with a favorable neurological outcome.

Conditions

• Heart Arrest, Out-Of-Hospital

Interventions

Type	Name	Description
DRUG	Calcium Chloride	Calcium chloride 5 mmol
DRUG	Sodium chloride 0.9%	Placebo

Timeline

• Start date: 2020-01-20
• Primary completion: 2021-04-15
• Completion: 2022-04-15
• First posted: 2019-11-06
• Last updated: 2022-07-25
• Results posted: 2022-02-25

Locations

1 site across 1 country: Denmark