Trials / Completed

CompletedNCT04152005

Endothelin Concentrations in a Population With Cardiovascular Disease and Periodonitis

Analysis of Endothelin Concentrations in a Population With Cardiovascular Disease and Periodontitis

Status: Completed
Phase: —
Study type: Observational
Enrollment: 165 (actual)

Sponsor: University of Messina · Academic / Other
Sex: All
Age: 21 Years – 71 Years
Healthy volunteers: —

Summary

Recently, a key role played in the ethiology of periodontitis has been highlighted by a Endothelin (ET-1). ET1 possess the ability to express surface antigens of endothelial and hematopoietic stem cells and to assist in maintaining vascular integrity and the repair mechanism of the endothelium. ET originate from bone marrow

Detailed description

The aim of the present study was to investigate the association between ET-1 in patients with periodontitis. Furthermore, the objective was to determine if the periodontal status influenced ET-1 levels.

Conditions

Serum; Disease

Interventions

Type	Name	Description
OTHER	Observation	Evaluation of ET-1 level and correlation of ET-1 levels with periodontal and cardiovascular disease

Timeline

Start date: 2016-01-01
Primary completion: 2018-09-25
Completion: 2018-09-30
First posted: 2019-11-05
Last updated: 2019-11-06

Locations

1 site across 1 country: Italy

Source: ClinicalTrials.gov record NCT04152005. Inclusion in this directory is not an endorsement.