Clinical Trials Directory

Trials / Completed

CompletedNCT04151212

A Phase I Clinical Trial of BAT5906 Injection in Patients With Wet Age-related Macular Degeneration

A Phase I Clinical Trial for BAT5906(Single-dose;for Injection) on Safety and Pharmacokinetics for Patients With Age-related Macular Degeneration

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
24 (actual)
Sponsor
Bio-Thera Solutions · Industry
Sex
All
Age
50 Years – 80 Years
Healthy volunteers
Not accepted

Summary

A Phase I Clinical Trial for BAT5906(single-dose;for injection) on Safety and Pharmacokinetics for Patients with Age-related macular degeneration.

Detailed description

The primary objective: To evaluate the safety and Pharmacokinetics of BAT5906 (single-dose Ophthalmic Intracireal Iinjection) in patients wAMD , when the injection dosage escalates. The Secondary objective: To evaluate the immunogenicity profile of BAT5906; To evaluate the pharmacodynamics and therapeutic efficacy profile of BAT5906.

Conditions

Interventions

TypeNameDescription
DRUGBAT5906 injectionSignal dose escalation starting from 0.3mg. Route of administration: intravitreal injection

Timeline

Start date
2018-10-30
Primary completion
2021-02-28
Completion
2021-04-30
First posted
2019-11-05
Last updated
2021-09-23

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT04151212. Inclusion in this directory is not an endorsement.