NCT04150601

Effects of SIMEOX on Flow and Volume in Healthy Subjects and Patients With COPD

Evaluation of SIMEOX Technology on Volumes and Flows Generated in Healthy Subjects and Patients With COPD

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 48 (actual)
• Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Academic / Other
• Sex: All
• Age: 45 Years – 90 Years
• Healthy volunteers: Accepted

Summary

This study will investigate the effects on the SIMEOX technology on flow and volume generated in healthy subjects and patients with COPD

Detailed description

This is a crossover study assessing the immediate physiological effects of SIMEOX and a PEP device on the exhalation phase in healthy subjects and patients with COPD. Participants will perform (1) a slow vital capacity, (2) a maximal expiration from total lung capacity to residual volume with SIMEOX, (3) a maximal expiration from total lung capacity to residual volume with a PEP device.

Conditions

• Healthy
• Pulmonary Disease, Chronic Obstructive

Interventions

Type	Name	Description
DEVICE	SIMEOX	SIMEOX is a device generating a succession of gentle depression at the mouth.
DEVICE	PEP	A PEP device (Pari-PEP) will be used to provoke a positive expiratory pressure while exhaling, thereby stabilizing the airways during expiration.
OTHER	Spontaneous Exhalation	A slow vital capacity maneuver will be performed according to the guidelines, from total lung capacity to residual volume

Timeline

• Start date: 2019-08-01
• Primary completion: 2021-11-16
• Completion: 2021-11-16
• First posted: 2019-11-05
• Last updated: 2023-11-21

Locations

1 site across 1 country: Belgium