Trials / Unknown
UnknownNCT04149093
The Association Between Calretinin and the Function of Ganglion Cells in Hirschsprung Disease
The Association Between Calretinin and the Function of Ganglion Cells in Long Segment and Total Hirschsprung Disease
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (estimated)
- Sponsor
- St. Justine's Hospital · Academic / Other
- Sex
- All
- Age
- 0 Years – 18 Months
- Healthy volunteers
- Not accepted
Summary
This study aims to compare the outcomes of patients with long segment Hirschsprung disease or total colonic aganglionosis who had negative calretinin staining and positive ganglion cells on the proximal resection margins to those who had both positive findings.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Calretinin staining | A paraffin-embedded hematoxylinphloxin-safran sections will be performed on tissue specimens of proximal resection margins to evaluate the presence or absence of ganglion cells. Immunohistochemistry (IHC) will then be done on paraffin-embedded sections for calretinin staining. |
Timeline
- Start date
- 2020-05-01
- Primary completion
- 2021-09-01
- Completion
- 2021-12-01
- First posted
- 2019-11-04
- Last updated
- 2021-03-17
Locations
1 site across 1 country: Canada
Source: ClinicalTrials.gov record NCT04149093. Inclusion in this directory is not an endorsement.