NCT04148053

Evaluation of Immune Cell Markers in Diagnosis of Tuberculosis

Evaluation of TB-antigen Responsive T Cell Markers in Diagnosis of Tuberculosis and Extrapulmonary Tuberculosis

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 500 (estimated)
• Sponsor: Tongji University · Academic / Other
• Sex: All
• Age: 7 Years – 90 Years
• Healthy volunteers: Accepted

Summary

Diagnosis of active and latent pulmonary tuberculosis, as well as extrapulmonary tuberculosis, is still a major challenge of TB control in China. This observational study aims to evaluate TB-antigen responsive T cell markers in the diagnosis of tuberculosis and extrapulmonary tuberculosis and try to find new prompt and cost-effective laboratory tests for active TB screening.

Detailed description

The enrolled patients will be grouped into active or latent tuberculosis according to the bacteriological evidence of TB. The TB-antigen responsive T cell markers will be examined. The performance of each T cell marker for the diagnosis of active TB will be systematically evaluated.

Conditions

• Tuberculosis Infection

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	TB-antigen responsive T cell markers	A blood test including a series of T cell markers which are responsive to TB antigens

Timeline

• Start date: 2018-11-01
• Primary completion: 2019-12-31
• Completion: 2020-03-01
• First posted: 2019-11-01
• Last updated: 2019-11-01

Locations

1 site across 1 country: China