NCT04148040

Per-oral Pyloromyotomy for Treating Infantile Hypertrophic Pyloric Stenosis

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Shanghai Zhongshan Hospital · Academic / Other
• Sex: All
• Age: 3 Years
• Healthy volunteers: Not accepted

Summary

Infantile hypertrophic pyloric stenosis (IHPS) is the most common condition for surgical treatment in infant. Traditionally, laparoscopic or open pyloromyotomy are the standard treatments. However, because of severe dehydration, electrolyte disturbance, and malnutrition, these patients have lower tolerance about surgery and recover more slowly than usual. We are going to study the per-oral pyloromyotomy (POP), also named as gastric per-oral endoscopic myotomy (G-POEM), which showed promising results for adult gastroparesis, for a novel application of treating IHPS.

Conditions

• Infantile Hypertrophic Pyloric Stenosis
• Pyloromyotomy

Interventions

Type	Name	Description
PROCEDURE	G-POEM	Per-oral pyloromyotomy (POP), also named as gastric per-oral endoscopic myotomy (G-POEM), for treating infantile hypertrophic pyloric stenosis (IHPS) has the following steps: mucosal incision, creation of submucosal tunnel, full-thickness pyloromyotomy, closure of the mucosal entry.

Timeline

• Start date: 2019-01-01
• Primary completion: 2020-12-01
• Completion: 2020-12-01
• First posted: 2019-11-01
• Last updated: 2019-11-14

Locations

1 site across 1 country: China