NCT04147585

Effects of an Intermittent Reduced Calorie Diet on Crohn's Disease

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 86 (actual)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to see how an Intermittent Calorie Reduced Diet (IRCD) that mimics fasting (also known as a fasting mimicking diet, FMD) effects inflammation in patients with mild to moderate Crohn's disease (CD). The diet may allow users to receive the benefits of fasting while also being able to enjoy food (the ingredients of which are GRAS (generally recognized as safe) by the Food and Drug Administration (FDA). Research on dietary interventions and CD are very limited. Diets that mimick fasting have been studied with support of the National Institute of Health and published in leading journals. This research investigates whether markers of inflammation decrease and/or quality of life increases after five-day periods of the IRCD, and may provide rationale for its use to treat CD.

Detailed description

As above

Conditions

• Inflammatory Bowel Diseases
• Crohn Disease
• Diet Modification

Interventions

Type	Name	Description
OTHER	Intermittent Reduced Calorie Diet (IRCD)	Three cycles of a 5-day Intermittent Reduced Calorie Diet over three months.

Timeline

• Start date: 2019-12-18
• Primary completion: 2024-03-12
• Completion: 2024-05-06
• First posted: 2019-11-01
• Last updated: 2025-04-17

Locations

1 site across 1 country: United States