Trials / Unknown
UnknownNCT04145245
A Randomized Controlled Trial to Assess the Effect of L-carnitine in Patients With Diabetic Peripheral Neuropathy to Relief Pain and Symptom Improvement
- Status
- Unknown
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 104 (estimated)
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh · Academic / Other
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
Diabetic Peripheral Neuropathy (DPN) is a common complication of diabetes mellitus. The prevalence rate is approaching towards a peak throughout the world including Bangladesh. The current intervention used in peripheral neuropathy does not bring satisfactory result. Recent trial shows that L-carnitine is effective and safe in DPN. So it is expected that L-carnitine may produce better effect in compared to other medicine used previously for alleviation of DPN.
Detailed description
: Diabetic peripheral neuropathy is one of the common complication of chronic diabetes mellitus, with a 30-50 % prevalence. Progressive development of pain, numbness in toes or feet and sensory motor disorders affects the patient's quality of life. The epidemic spread of the disease has raised concern among physicians and researchers. A variety of agents or medicines with potential effect have been studied to control development of peripheral neuropathy. The existing management are yet unsatisfactory. Recent studies have suggested that L-carnitine is potential to alleviate symptoms in patents with diabetic neuropathy. Previous trial also indicated the efficacy and safety of L-carnitine on diabetic neuropathy. This limitations have led to search for an effective and tolerable option by placebo controlled trial.The present study is an attempt to investigate the effects of carnitine on pain and symptom improvement of diabetic peripheral neuropathy.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Levocarnitine | Levocarnitine syrup- oral supplementation about 1500 mg/day for 10 weeks |
Timeline
- Start date
- 2018-04-17
- Primary completion
- 2019-12-30
- Completion
- 2020-02-28
- First posted
- 2019-10-30
- Last updated
- 2019-10-30
Locations
1 site across 1 country: Bangladesh
Source: ClinicalTrials.gov record NCT04145245. Inclusion in this directory is not an endorsement.