Trials / Recruiting
RecruitingNCT04141020
Effect of Sirolimus on Molecular Alterations in Cerebral Aneurysms
- Status
- Recruiting
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 80 (estimated)
- Sponsor
- University of Miami · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The objective of this study is to explore the effects of Sirolimus on the underlying molecular alterations of cerebral aneurysms.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Microsurgical clipping | Standard of care microsurgical clipping of an unruptured cerebral artery aneurysm. |
| PROCEDURE | Endovascular treatment | Standard of care endovascular treatment of an unruptured cerebral artery aneurysm. |
| DRUG | Sirolimus | Daily oral Sirolimus 2 mg tablets, adjusted as necessary per treating physician. |
Timeline
- Start date
- 2021-10-27
- Primary completion
- 2026-11-01
- Completion
- 2026-11-01
- First posted
- 2019-10-28
- Last updated
- 2026-03-23
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT04141020. Inclusion in this directory is not an endorsement.