NCT04137068

Sedentary Behavior, Cardiovascular Function, and Sleep

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Oregon Health and Science University · Academic / Other
• Sex: All
• Age: 20 Years – 80 Years
• Healthy volunteers: Accepted

Summary

This is an interventional study that will examine how sedentary behavior (decreased physical inactivity) over time affects cardiovascular health (i.e. heart rate and blood pressure) and sleep quality/duration.

Detailed description

PRIMARY OBJECTIVES: 1\. To test the hypothesis that two weeks of sedentary behavior will progressively impair vascular endothelial function. 2: To test the hypothesis that increasing sedentary behavior will decrease total sleep duration and sleep efficiency. 3: To test the hypothesis that two-weeks of sedentary behavior will progressively increase 24-h blood pressure and reduce nocturnal blood pressure dipping. OUTLINE: After a baseline period, participants will become more inactive and also come in for 4-h uninterrupted sitting visits. Cardiovascular, activity, and sleep measures will be taken throughout.

Conditions

• Sedentary Behavior
• Cardiovascular Function
• Sleep

Interventions

Type	Name	Description
BEHAVIORAL	Reduced Activity	Participants reduce their activity level to \<5,000 steps/day and \<50 % of baseline steps.

Timeline

• Start date: 2019-11-13
• Primary completion: 2023-03-31
• Completion: 2023-03-31
• First posted: 2019-10-23
• Last updated: 2022-08-05

Locations

1 site across 1 country: United States