Trials / Completed
CompletedNCT04135209
Optical Coherence Tomography Angiography in Myopic Patients
Evaluation of Macular Microvasculature in High Myopia Using Optical Coherence Tomography Angiography
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 55 (actual)
- Sponsor
- Minia University · Academic / Other
- Sex
- All
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
The aim of this study is to investigate the macular microvascular network alterations in high myopic eyes using optical coherence tomography angiography.
Detailed description
High myopia is defined as a refractive error equal to or more than -6 D, and/or axial length equal to or more than 25.5 mm².Axial elongation of the globe and subsequent stretch of the retina leads to sight threatening complications. Quantitative measurements of retinal vasculature in the healthy eye have been reported using several in vivo and in vitro techniques, including confocal microscopy, fluorescein angiography (FA), and swept-source optical coherence tomography (ssOCT) angiography. The aim of this study is to investigate the macular microvascular network alterations in high myopic eyes using optical coherence tomography angiography. This cross-sectional prospective study included 75 eyes of 54 patients, they were recruited from the outpatient clinic of ophthalmology department of El-Minia university hospital.They were divided into two groups, group A included 25 normal eyes of 25 patients. Group B included 50 myopic eyes of 30 patients. All patients subjected to history taking and full ophthalmological examination in addition to axial length measurment before performing OCTA.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Optical coherence tomography angiography OCTA | Macular scanning using regular structural OCT as well as microvasculature analysis using OCTA |
Timeline
- Start date
- 2018-01-01
- Primary completion
- 2019-01-01
- Completion
- 2019-06-01
- First posted
- 2019-10-22
- Last updated
- 2019-10-22
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT04135209. Inclusion in this directory is not an endorsement.