NCT04133428

Prospective Observational Study of the Sacubitril-Valsartan Treatment Effectiveness.

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Fundación Pública Andaluza para la gestión de la Investigación en Sevilla · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this prospective study is to demonstrate if there is any difference in the treatment response to Sacubitril-Valsartan depending on the ventricular disfunction ethiology in patients with severe systolic disfunction heart failure.

Conditions

• Heart Failure

Interventions

Type	Name	Description
DRUG	Sacubitril-Valsartan	Evaluation of the Sacubitril-Valsartan treatment effectiveness. As there are three possible doses, during the first 30 days of treatment 3 evaluations will be carried out (every 10 days) for dose titration based on safety and tolerability as well as a blood test the 30rd day of treatment. Afterwards the patient will be evaluated after 3 and 6 months of treatment with a blood test and in the final visit (6 months) an echocardiography will be carried out and the final clinical evaluation will be made.

Timeline

• Start date: 2019-04-04
• Primary completion: 2021-04-04
• Completion: 2021-07-15
• First posted: 2019-10-21
• Last updated: 2020-02-07

Locations

1 site across 1 country: Spain