NCT04132323

Low Concentrate Detergents Versus Hypertonic Glucose for the Treatment of Telangiectasia

Clinical Efficacy of Low Concentrate Detergents Versus Hypertonic Glucose for the Treatment of Telangiectasia: a Prospective Randomized Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 172 (actual)
• Sponsor: Derzhavin Tambov State University · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Not accepted

Summary

Using of low concentrate sodium tetradecyl sulfate for sclerotherapy of telangiectasias should be no less effective than hypertonic glucose, and have a comparable frequency of adverse events.

Detailed description

For sclerotherapy of telangiectasias are used detergents. These are aggressive substances, which have a high frequency of adverse events. According to histological studies the safest concentration for the treatment of telangiectasias is less than that specified in the official instructions. The concentration of sodium tetradecyl sulfate 0.15% was effective and did not cause any adverse reactions in the treatment of telangiectasias from 0.8 to 1 mm in diameter. Small telangiectases (0.5 mm or less) require the treatment with the less aggressive sclerosing agent. Perhaps, the sodium tetradecyl sulfate 0.15%, 0.1% or even 0.05% and hypertonic glucose may be more effective and safe in this situation.

Conditions

• Sclerotherapy

Interventions

Type	Name	Description
PROCEDURE	Sclerotherapy	Examination, photographing, inclusion in the study, signing of informed consent, randomization, diameter measurement, sclerotherapy according to the randomization group

Timeline

• Start date: 2019-10-25
• Primary completion: 2022-03-15
• Completion: 2022-03-15
• First posted: 2019-10-18
• Last updated: 2023-10-10

Locations

1 site across 1 country: Russia