NCT04132180

Early Versus Late Upper Extremity Mobilization After Autograft

The EXTREMA Trial: The Impact of Early Versus Late Upper Extremity Mobilization After Split Thickness Skin Autograft on Wound Healing in Adult Burn Patients - A Single Center Non-Inferiority Randomized Clinical Trial

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 2 (actual)
• Sponsor: Sunnybrook Health Sciences Centre · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Rationale: There is currently no observational study or randomized clinical trial published evaluating the impact of early versus late mobilization in the upper extremity after split thickness skin autograft. As the current post-operative care protocols vary based on physician preference, evidence is needed to optimize post-operative rehabilitation protocols guided by evidence which optimize wound healing, extremity range of motion, graft site pain, as well as minimize risks of complications and length of stay in hospital. Objective: To determine if early mobilization is non-inferior to late mobilization of the upper extremity after split thickness skin autograft with regards to wound healing measured as percent graft take on post-operative day 5 in adult burn patients.

Conditions

• Burns

Interventions

Type	Name	Description
OTHER	Early Mobilization	Range of motion exercises of the upper extremity will be performed under the guidance of the physical therapy team starting on post-operative day 1.
OTHER	Late Mobilization	The patient's grafted upper extremity will be immobilized using an elbow flexion blocking splint until post-operative day 5.

Timeline

• Start date: 2018-08-14
• Primary completion: 2022-02-10
• Completion: 2022-02-10
• First posted: 2019-10-18
• Last updated: 2022-03-02

Locations

1 site across 1 country: Canada