NCT04130971

Predicting Colorectal Cancer - Tissue Samples to Evaluate Tumour Characteristics and Treatment Response

Predict - a Translational Study to Predict Tumour Response to Neoadjuvant Treatment

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 800 (estimated)
• Sponsor: Sahlgrenska University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

All adult patients with colorectal cancer presenting within the Sahlgrenska University Hospital or treated at any time at Sahlgrenska University Hospital are eligible and will be asked to participate. We already have biopsies taken at surgery in patients that receive surgery, but this study will include all patients and the biopsies will be taken during endoscopy for diagnosis of the primary tumour. Biopsies will then be taken during follow-up exams prior surgery but after neoadjuvant treatment. Biopsies will also be taken during surgery and in cases where surgery is not necessary biopsies will be taken regularly during follow-up exams. Blood samples and in relevant cases urinary samples and mouth swabs will be taken at all timepoints when biopsies are taken. If it is not possible to take biopsies prior treatment blood samples will still be drawn.

Conditions

• Colorectal Neoplasms

Interventions

Type	Name	Description
OTHER	No intervention, just observation	No intervention, just observation of the differences between groups and within patients.

Timeline

• Start date: 2019-02-01
• Primary completion: 2025-12-31
• Completion: 2027-12-31
• First posted: 2019-10-18
• Last updated: 2023-11-07

Locations

1 site across 1 country: Sweden