NCT04130581

Brain Stimulation During Arm Immobilisation

Exercising the Motor Cortex Using Brain Stimulation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Lancaster University · Academic / Other
• Sex: Male
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

The research project explores how non-invasive brain stimulation can be used to detect and ameliorate loss of muscle strength after inactivity. At present, there is a limited understanding of how to maintain muscle strength during inactivity. Increasing evidence indicates that reduction in muscle strength following immobilisation is associated with reduced cortical motor output. Therefore, the aim of the study is to test if brain stimulation, can maintain cortical motor output and ameliorate the loss of muscle strength following immobilisation.

Conditions

• Muscle Loss

Interventions

Type	Name	Description
OTHER	Transcranial Magnetic Stimulation (TMS)	TMS is a safe and non-invasive technique, which involves the generation of brief magnetic pulses applied to the head through a coil. The magnetic pulses pass through the scalp and skull and induce weak electric currents in the neural tissue directly underneath the coil. When TMS is applied in repetitive, patterned trains of pulses (rTMS), it can induce cortical plasticity specifically in the targeted brain region.

Timeline

• Start date: 2018-05-14
• Primary completion: 2020-01-31
• Completion: 2020-01-31
• First posted: 2019-10-17
• Last updated: 2020-02-19

Locations

1 site across 1 country: United Kingdom