Trials / Recruiting
RecruitingNCT04126148
Breathing-Maneuver-Induced Myocardial Oxygenation Reserve Validated by FFR (B-MORE)
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 350 (estimated)
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The study aims to determine a diagnostic marker for regionally impaired myocardial oxygenation response in patients with suspected coronary artery stenosis.
Detailed description
This observational applied research international study aims to assess the validity of breathing maneuvers as a vasoactive maneuver and Oxygenation-Sensitive Cardiac Magnetic Resonance Imaging (OS-CMR) in a patient population. OS-CMR results will be compared to the clinical gold standard of Fractional Flow Reserve (FFR) and instant wave-free ratio (iFR) as a secondary objective, to determine if this non-invasive, no pharmaceutical agent imaging technique can identify areas of oxygenation deficit in myocardium perfused by a stenosed coronary artery.
Conditions
Timeline
- Start date
- 2019-07-04
- Primary completion
- 2024-12-01
- Completion
- 2024-12-01
- First posted
- 2019-10-15
- Last updated
- 2024-10-24
Locations
1 site across 1 country: Canada
Source: ClinicalTrials.gov record NCT04126148. Inclusion in this directory is not an endorsement.